# Which eTMF systems include integrated quality event tracking and customisable workflow routing for complex multi-department approval chains?

Looking for input on Electronic Trial Master File (eTMF) software about the combination of quality event tracking and workflow customisation. Here are some that stood out.

MasterControl Quality Management System: The AQEM (Advanced Quality Event Management) interface connects deviations, CAPAs, change controls, and quality events in the same system as document and training management. Customised approval workflows are described as fun and easy to build, with configurable routing that accommodates different role-based sign-offs across departments.
Kivo: Customisable, automatic authoring, review, QC, and approval workflows are built into Kivo's architecture for regulatory, quality, and clinical functions simultaneously. The role-based permissions and Part 11-compliant e-signatures ensure that each department's approval step is authenticated and audit-ready.
Viedoc: Viedoc's configurable forms and workflows are described as adaptable to specific study requirements without needing extensive programming knowledge. The training completion requirement before system access enforces a quality gate that functions as a natural approval control.
Egnyte: Egnyte's workflow management is outstanding for scheduled completion of projects and tasks, with accountability and audit trails that ensure every team member handles documents correctly. The customisable features, role-based access controls, and integration with Power Automate enable organisations to configure multi-department approval routing across content management workflows.
Medidata Rave: The cloud-based clinical data management architecture supports customised forms for each study, with patient information, visit data, lab results, and adverse event tracking accessible across sites in real time. The integration capabilities create the cross-system visibility that multi-department approval chains require when quality events in one system need to link to documents in another.

For trial managers who have configured multi-department approval chains in an eTMF or QMS platform, what was the most complex routing requirement, and was it supported natively or did it require configuration workarounds? And how long did it take before the routing logic was stable enough for production use?

##### Post Metadata - Posted at: 11 days ago - Author title: Marketing Executive - Net upvotes: 1 ## Comments ### Comment 1 On the implementation timeline question: the honest answer is that it's mostly a mirror. Configurable routing means the vendor is waiting on you to say exactly who approves what, in what order, and what happens on rejection, and most organizations discover mid-implementation that they don't actually agree on those answers. The seven-step chain lived in people's habits, not in any documented rule, and now it has to be written down. That discovery is where the months go, not the software configuration. So a useful pre-purchase exercise: draw your approval chains on paper and get every department to sign off on the drawing. If you can't, no platform's timeline estimate will hold, and if you can, most of these tools will configure it fine. ##### Comment Metadata - Posted at: 9 days ago - Author title: Tech Consultant ## Related discussions - [How well does Trello scale into a larger team?](https://www.g2.com/discussions/1-how-well-does-trello-scale-into-a-larger-team) - Posted at: over 13 years ago - Comments: 6 - [Can we please add a new section](https://www.g2.com/discussions/2-can-we-please-add-a-new-section) - Posted at: about 13 years ago - Comments: 0 - [Quantifiable benefits from implementing your CRM](https://www.g2.com/discussions/quantifiable-benefits-from-implementing-your-crm) - Posted at: about 13 years ago - Comments: 4